Mass spectrometry (MS) is an analytical technology that measures the mass-to-charge ratio (m/z) of one or more molecules present within a sample and determines their relative abundance. Mass spectrometry is pervasive within life sciences to detect, identify and quantify compounds within a sample and elucidate the structure or chemical properties of certain molecules. The technology involves ionizing the sample and then stratifying the generated ions based on mass-to-charge ratio to generate a mass spectrum, which is done using a mass spectrometer. In this introductory post, we will briefly discuss how mass spectrometry works and point out some intricacies of MS data.
By Marc Claesen on May 30, 2020
Mass spectrometry imaging (MSI) is rapidly being adopted in drug development, biomarker discovery and clinical diagnostics. In this post, we provide a high-level introduction to MSI technology along with the specific challenges and opportunities it brings in terms of data analysis. This post focuses on introducing some nomenclature and describing the main aspects about working with MSI data from a data science perspective.
By Marc Claesen on May 31, 2020